Gay couple, cat Stimpy and chihuahua Renk, working as disc jockies (top) at W. A.C.K.; and the asthmatic Ren Hoek (middle) sick in bed.
No less an authority as their creator John Kricfalusi stated they were gay, and it's pretty obvious in a number of episodes, like "Insomniac" in which Ren largely about their bedroom habits.
Violently psychotic chihuahua Ren Hoek and mentally deficient sweet-natured obese manx Stimpson J. Cat were the comedy team at the heart of The Ren and Stimpy Show (1991-1996).
These cartoons started out truly maniacal and at the fringe, with Kricfalusi at the helm, but he lost control of his creation and by the last of these cartoons Ren and Stimpy were acting increasingly like Hanna-Barbera animals.
Kricfalusi would later bring back some of his original animation team for a revamping of Ren and Stimpy with ten new episodes first aired on Spike TV between 2003 and 2004, and the couples' homosexuality was finally rendered overt.
Below is about half of the episode that introduced Ren and Stimpy's hit song "Happy Happy Joy Joy." The crappiness of the copy is somehow in keeping with the spirit of the show. The episode shows Ren forced into a mind-control device that makes him perpetually happy, but still with the edge of psychosis that is central to his nature.
And see also the following video "Who Is Stinky Wizzleteats?"
which is a behind-the-scenes look at
the origins of the "Happy Happy Joy Joy" song